Tibetan Mastiffs Bred with Mountain Wolves to Survive at Super-High Altitudes

Tibetan mastiffs can thrive at high altitudes, where the thin air would kill other breeds. And now, according to a paper published July 30 in the journal Molecular Biology and Evolution, we know why: At some point in the past, the dogs interbred with Tibetan wolves, and their descendants inherited gene mutations that code for two amino acids ⁠— small pieces of a protein ⁠— that make Tibetan mastiffs' blood better at capturing and releasing oxygen.  


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